What is Menatetrenone / Vitamin K2 ?
Vitamin K is a class of quinone compounds, including five different structures of the compound, namely vitamins K1, K2, K3, K4, K5. Vitamin K2 is a series of compounds, light yellow crystals, mainly synthesized by intestinal bacteria, a total of 14 kinds according to the length of isoprene side chain on C3, mainly used in the treatment of osteoporosis is vitamin K2(20), namely tetramethylene naphthoquinone. Studies have shown that tetramethylene menaphthoquinone has osteogenic effects, promoting calcium metabolism, and inhibiting bone resorption caused by osteoclasts, thereby increasing bone density and preventing osteoporosis. Tetramethylene naphthoquinone is an oil-like substance, and it is easy to decompose by light, so it is suitable for soft capsule formulation.
Wholesale High Quality Menaquinone Powder Vitamin K2 MK4
Vitamin K2 is a fat soluble vitamin mainly synthesized by gut bacteria and also present in some animal meat and fermented products, such as animal liver, fermented dairy products, and cheese. Among them, the most abundant source of VK2 is natto, which is divided into 14 different forms, including MK-2, MK-4, MK-7, and MK-8. MK-7 has been found to be more effective, bioavailable, and also has a longer half-life. MK-7 has a more effective effect in activating osteocalcin and has a longer residence time in the blood circulation, mainly playing a crucial role in cell growth and metabolism, as well as preventing calcification of cardiovascular, cerebrovascular, and renal vessels.
Vitamin K2 is the only form of vitamin K with biological activity, which is mainly used to accelerate coagulation, maintain coagulation time, and treat the hemorrhage caused by vitamin K deficiency. It is also used for other healthcare purposes.
Vitamin K is a derivative of a naphthoquinone group having the biological activity of chlorophyllin. Naturally occurring vitamins K1 and K2, vitamin K1 is widely found in green plants and is an important source of vitamin K in foods; vitamin K2 is mainly synthesized by intestinal bacteria.
Synthetic vitamin K3, K4, K5, K7 and the like. Vitamin K2 is biologically active in animals,and both vitamin K1 and vitamin K3 are converted to vitamin K2 to function. The three forms of vitamin K are converted into vitamin K2 in the liver and are absorbed and utilized together with vitamin K2 synthesized by gastrointestinal microorganisms.
Vitamin K2 is a generic term for a series of terpene side chain compounds containing a 2-methyl-1,4-naphthoquinone core and a C3
position with a different number of isoprene structural units, depending on the side chain of the terpene. The number of carbon
elements can be classified into K2 (10), K2 (20), K2 (35), K2 (40), and the like.
Vitamin K2 is a fat-soluble vitamin, a derivative of the naphthoquinone group with biological activity of chlorophyll, and is one
of the important vitamins in the human body.
What is Vitamin K?
Vitamin K is a fat-soluble vitamin needed to produce blood-clotting factors, such as prothrombin, that prevent unchecked bleeding or hemorrhaging throughout the body. It also helps strengthen the body's bones and capillaries.
Vitamin K comes in three forms: phylloquinone, menaquinone, and menadione. Phylloquinone, or K1, is found in green leafy vegetables, and helps bones absorb and store calcium. One recent study showed that increased amounts of vitamin K in the diet might lower the risk of hip fracture; over time, a shortage of vitamin K could lead to osteoporosis.
Menaquinone, or K2, is manufactured in the body by naturally occurring intestinal bacteria. People that regularly take antibiotics or have a medical condition that upsets the balance of bacteria in the intestine are at risk of developing a vitamin K deficiency. Menadione, or vitamin K3, is an artificial form of vitamin K, which is water-soluble and more easily absorbed by people who have problems with fat absorption.
Vitamin K Benefits
Vitamin K2 is a fat-soluble vitamin,it is needed to manufacture prothrombin, a substance essential for the normal clotting of blood.
1.Vitamin K2 is being used to cure haemorrhage caused by VK2 deficiency; promotes the formation of thrombin, accelerates blood clotting, maintains proper clotting time; also used as quick coagulant in surgeries or first aids.
2. Vitamin K2 is being used to treat the degenerative bone disease osteoporosis.; VK2 produces a specific protein known as osteocalcin which can bind calcium, therefore to increase the density of bones and to prevent fracture.
3. Vitamin K2 can prevent the disease of hepatocellular carcinoma in women with viral cirrhosis.
4. Vitamin K2 has function of diuresis, promotes the detoxifcation of liver and lowering the blood pressure.
Vitamin K Mode of Action
(1) treatment and prevention of osteoporosis, vitamin K2 generate bone protein, and then together with the calcium of bone formation, increase bone density and prevent fractures.
(2) Vitamin K2 can prevent progression to liver cirrhosis.
(3) the lack of treatment of hemorrhagic disease of vitamin K2, and promote the formation of prothrombin, accelerated blood clotting, maintain normal clotting time.
(4) with a diuretic, strengthen the liver's detoxification function, and can lower blood pressure.
Vitamin K Dosage
Vitamin D can be used for sandwich hard candy, and the amount used is 2000-6000mg/kg;
The amount of use in high-iron cereals and their products is 800-1000 mg/kg;
The amount used in infant food is 300-500 mg/kg;
The amount used in canned fruit is 200-400 mg/kg;
The amount used in drinks and milk drinks is 120-240 mg/kg;
The amount used in the puree is 50 to 100 mg/kg.
Specification:Vitamin K2 MK7 1.3% Powder
Vitamin K2 is also called menaquinone, K stands for Koagulation. Vitamin K2 is pale yellow to white powder, insoluble in water, soluble in organic solvents and vegetable oil.
Vitamin K2 has several different subtypes, the most important ones are short-chain MK-4 and long-chain MK-7. M stands for menaquinone, the K stands for vitamin K, the number represents the number of isoprenoid side chain residues.
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tem Name
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Vitamin K2
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CAS NO.
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11032-49-8 |
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Apparence
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yellow powder
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Purity
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99%
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package
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Aluminum Bag;Drums
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Advantage
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OEM;ODM
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Certificate
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GMP/ISO9001
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Payment
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Trade Assurance;L/C;T/T;Western Union
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Warranty
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2 Years If Keep It Well
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Items
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Standard
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Results
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Characters
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Light yellow Powder |
Qualified
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Identification
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Meets the requirements
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Qualified
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Appearance of solution
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Meets the requirements
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Qualified
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Organic volatile impurities
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Meets the requirements
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Qualified
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Heavy metals
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≤0.002%
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Qualified
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Loss on drying
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≤0.5%
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0.18%
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Residue on ignition
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≤0.1%
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0.05%
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Assay
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98.0%
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98.5%
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CONCLUSION:
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This is certify that the product complies to the standards
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Vitamin K2 (Menaquinone) is a very important fat-soluble vitamin that plays an important role in protecting the heart and brain and building strong bones. Menatetraene quinone, also known as vitamin K2, is a fat-soluble vitamin and one of the important vitamins that are indispensable to the human body. Its main function is to increase the bone mass of osteoporosis patients and is used to prevent and treat osteoporosis.
1. It can treat vitamin K deficiency hemorrhage, promote the formation of prothrombin, accelerate coagulation, and maintain normal coagulation time.
Vitamin K2 has biological activity in animals, and both vitamin K1 and vitamin K3 need to be converted into vitamin K2 to function. All three forms of vitamin K are converted into vitamin K2 in the liver and absorbed together with vitamin K2 synthesized by gastrointestinal microorganisms.
2. Vitamin K2 can promote liver cell proliferation and liver regeneration, preventing cirrhosis from transforming into liver cancer,
3. The most significant health effect of VK2 is to prevent osteoporosis and vascular calcification, which is used to treat and prevent osteoporosis. Vitamin K2 can promote the generation of bone proteins, which together with calcium can generate bone, increase bone density, and prevent fractures.
Vitamin K2 promotes calcium metabolism and has a positive effect on preventing and treating osteoporosis. Research confirms that vitamin K can act on osteoblasts, promote bone tissue calcification, and inhibit osteoclast to cause bone absorption, thus increasing bone density, which can not only prevent but also cure osteoporosis; The lack of VK2 in the human body prevents calcium ions from depositing into the bones. The traditional calcium supplementation methods are calcium and vitamin D3, which cannot bring calcium into the bones. "People often do not lack calcium, but cannot absorb and bring calcium into the bones." Therefore, the correct calcium supplementation method should be VD3+VK2.
4. Vitamin K2 has diuretic, liver enhancing detoxification functions, and can lower blood pressure.
5. Reduce the frequency and severity of muscle spasms,
Improve symptoms of rheumatoid arthritis,
6. Relieve peripheral neuropathy and nervous system disease such as Parkinson's disease,
Improve the complications of diabetes and treat psoriasis, etc,
In addition, as long as the body has appropriate probiotics, it can also produce vitamin K through colonic bacterial metabolism. Therefore, it is recommended that partners with severe VK deficiency supplement probiotics additionally.
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