Chemcals Product Food Additives Microcrystalline Cellulose Powder

• CAS No.: 9004-34-6
• Formula: (C12h20o10)N
• EINECS: 232-674-9
• Product: Microcrystalline Cellulose
• Loading: Tianjin
• Colour: White
• Model NO.: Microcrystalline cellulose
• Capacity: 5000mt/Month
• Transport Package: 25kg/Bag
• Specification: 99%
• Trademark: ZHUOFENG
• Origin: China Mainland
• HS Code: 3912900000
• Production Capacity: 5000mt/Month

Product Description

Microcrystalline cellulose (MCC) is a kind of straight chain polysaccharide bound by β-1, 4-glucoside bond, which is a very fine, free-flowing, short rod or powdery porous particle of natural cellulose hydrolyzed by dilute acid to limit degree of polymerization (LODP). Composed of white, odorless, tasteless crystalline powder.

Microcrystalline  Cellulose is a naturally non-caloric indigestible dietary fiber that is widely used in food, cosmetics and pharmaceutical industries. Its primary purpose is as an anticaking agent in food and pharmaceutical processing.

 

 

 

 

Microcrystalline Cellulose 101 serves a primary function as a binder and filler in pharmaceutical formulations. Its fibrous particles exhibit exceptional compressibility, enabling the production of mechanically robust tablets. As a binder, MCC 101 enhances the cohesion of powder blends during compression, ensuring the formation of tablets with uniform hardness and disintegration characteristics. Additionally, its role as a filler contributes to the uniform distribution of the active pharmaceutical ingredient, facilitating accurate dosing and promoting tablet homogeneity.

 

The applications of Microcrystalline Cellulose 101 in pharmaceutical formulations are diverse and encompass a wide range of dosage forms. In tablet manufacturing, MCC 101 is extensively used to produce direct compression tablets or as a component in wet granulation processes. Its compatibility with various drug formulations makes it suitable for different therapeutic classes. Moreover, MCC 101 finds application in the development of oral disintegrating tablets, where its fast disintegration properties contribute to rapid drug release and improved patient compliance. The versatility and reliability of MCC 101 make it a cornerstone excipient in modern pharmaceutical formulations.

 

 

Product name	Microcrystalline cellulose		TEST DATE	1. 27, 2022
QUANTITY	1000kg		MANUFACTURE DATE	1. 25, 2022
PACKING	20kg/bag		EXPIRY DATE	1. 24, 2024
TEST ITEMS		SPECIFICATION			RESULTS
Appearance		White or almost white,fine or granular powder.			Conform
Identification A		Conform			Conform
Identification B		The degree of Polymerization≤350			211
Granulometry		Remains 60 mesh≤1% Remains 200 mesh≤30%			0.1% 9.1%
Conductivity		≤75us/cm			33us/cm
PH value		5.0-7.5			6.4
Loss on drying		≤7.0%			3.1%
Residue on ignition		≤0.10%			0.02%
Water Soluble Substances		≤0.25%			0.12%
Ether-Soluble Substances		≤0.05%			0.02%
Heavy metal		≤0.001%			<0.001%
Microbial limits
TAMC		≤1000cfu/g			25CFU/g
TYMC		≤100cfu/g			<10CFU/g
Escherichia coli		Absent			Absent
Salmonella species		Absent			Absent
Staphylococcus aureus		Absent			Absent
Pseudomonas aeruginosa		Absent			Absent
Conclusion:		Conform

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