Customization: | Available |
---|---|
Type: | L- Proline |
Chemical Character: | Neutral |
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1. Used in biochemical research, medicine for malnutrition, protein deficiency, gastrointestinal diseases, burns and postoperative protein supplement.
2. Nutritional supplements. Flavor agent, co-heated with sugar, amino - carbonyl reaction, can produce special flavor substances. According to GB 2760-86, it can be used as a spice.
3. Used for amino acid injection, complex amino acid infusion, food additives, nutrition replenishment liquid, etc.
4. Pharmaceutical raw materials and food additives.
5. Proline itself is chiral, so it is commonly used as a chiral lead reagent in the total synthesis of some natural products;
At the same time, as an optically active adjuvant, proline plays an important role in asymmetric total synthesis
[1]. Asymmetric catalysis When proline is used as the chiral catalyst, the carbonyl compound can undergo asymmetric Michael reaction, and the product is β-hydroxyaldehyde (or ketone) (Formula 1)
[2]. Under the catalysis of L-proline, the nitroso compound can undergo α-amine oxidation with the carbonyl compound (Equation 2)
[3]. L-proline can also catalyze asymmetric Diels-Alder reactions (Equation 3)
Item | Limit | Results |
Appearance | White crystalline powder | White crystalline powder |
Assay | 99.0%-101.0% | 99.03% |
Specific rotation(a)D20(C=2, H2O ) |
-0.3°to 0.3
|
0° |
Ammonium (NH4) | NMT 0.02% | < 0.02% |
Sulfate(SO4) | NMT 0.1% | < 0.1% |
Heavy metals (as Pb) | NMT 10 ppm | <10 ppm |
Iron (Fe) | NMT 10 ppm | 8 ppm |
As2O3 | NMT 1 ppm | <1 ppm |
Loss on drying | NMT 0.50% | 0.39% |
Residue on ignition | NMT 0.1% | 0.08% |
Remarks | Store in well closed container and in dry and cool place |
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